Development and Evaluation of Fast Disintegrating Tablets Containing Lornoxicam Solid Dispersions

Formulation & Evaluation of Oral Disintegrating Tablets of Lamotrigine Solid Dispersions

Lamotrigine is used in the treatment of CNS disorders, particularly epilepsy; pain; oedema; multiple sclerosis and psychiatric indications including bipolar disorder. Lamotrigine belongs to biopharmaceutical classification systems, BCS class II (Low solubility & High permeability). In addition, it requires immediate therapeutic action hence the main objective of this study is to improve the sol...

Optimization and Formulation Design with In-Vitro Evaluation of Fast Disintegrating Tablets Containing Candesartan Solid Dispersions

The aim of this study was to assess the effects of processing parameters on the release of solid dispersion formulation from a fast dissolving tablet dosage form. Graphical and mathematical analysis such as the response surface methodology (RSM) and multiple response optimizations utilizing the polynomial equation were used to search for the optimal formulation and to quantify the effect of eac...

formulation & evaluation of oral disintegrating tablets of lamotrigine solid dispersions

lamotrigine is used in the treatment of cns disorders, particularly epilepsy; pain; oedema; multiple sclerosis and psychiatric indications including bipolar disorder. lamotrigine belongs to biopharmaceutical classification systems, bcs class ii (low solubility & high permeability). in addition, it requires immediate therapeutic action hence the main objective of this study is to improve the sol...

Development and Evaluation of Fast Disintegrating Extended Release Tablets Containing Antihypertensive Drug"

Objective: The aim of this work was preparing once daily fast disintegrating tablets to handle easily for adult hypertensive patients who have difficulty in swallowing. Methods: Solid dispersions bisoprolol hemifumarate (SD-BH) was prepared by using EC and HPMC in different ratios. A 3* 22 full factorial design was used to investigate the main formulation parameters (different fillers, binder d...

formulation and evaluation of domperidone fast disintegrating tablets and its taste masking using solid dispersion technology